Author(s): Daniela Rossi | Anna Carnevale Baraglia | Massimo Serra | Ornella Azzolina | Simona Collina
Journal: Molecules
ISSN 1420-3049
Volume: 15;
Issue: 9;
Start page: 5928;
Date: 2010;
Original page
Keywords: (Z)-3 | 3-trisubstituted α | β-unsaturated methyl esters | aryl-alkyl ketones | Horner–Wadsworth-Emmons reaction | microwave-assisted reactions
ABSTRACT
A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-α,β-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds.
Journal: Molecules
ISSN 1420-3049
Volume: 15;
Issue: 9;
Start page: 5928;
Date: 2010;
Original page
Keywords: (Z)-3 | 3-trisubstituted α | β-unsaturated methyl esters | aryl-alkyl ketones | Horner–Wadsworth-Emmons reaction | microwave-assisted reactions
ABSTRACT
A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-α,β-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds.