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Electrochemical Bioencapsulation of Nanomaterials into Collagen for Biomedical Applications

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Author(s): Xingguo Cheng | Vasiliki Poenitzsch | Lauren Cornell | Christopher Tsao | Thomas Potter

Journal: Journal of Encapsulation and Adsorption Sciences
ISSN 2161-4865

Volume: 03;
Issue: 01;
Start page: 16;
Date: 2013;
Original page

Keywords: Nanomaterials | Electrochemical | Bioencapsulation | Collagen | Biomedical Applications

ABSTRACT
  Here we reported a novel electrochemical encapsulation method to encapsulate various nanomaterials and bimolecules into collagen. The electrochemical encapsulation process involves assembling of collagen along with Nano/bio materials using an isoelectric focusing mechanism. We have showed that a wide range of Nanomaterials such as carbon nanotubes, polymeric nanoparticles, magnetic calcium phosphate nanoparticles and biomolecules can be encapsulated into collagen. These novel collagen-based composite materials possess improved electric, mechanical, antimicrobial, magnetic, bioactive properties. Thus, this novel electrochemical encapsulation process offers a means to fabricate novel biomaterials for various biomedical applications such as tendon/ligament, nerve, skin tissue engineering, tendon/ligament to bone grafts, and sutures, etc.
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