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Empleo de la diafiltración en el lavado de cultivos de Leptospira interrogans canicola canicola para la producción de la vacuna vax-SPIRAL Use of diafiltration in the lavage of cultures of Leptospira interrogans canicola canicola for the production of vaccine vax-SPIRAL

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Author(s): Kenia Fernández Enrique | José Daniel Benítez Zamora | Raúl Boué Gutiérrez | Florinda Hernández Torres | Janet Airado | Damián Rojo Hernández

Journal: Revista Cubana de Medicina Tropical
ISSN 0375-0760

Volume: 57;
Issue: 1;
Start page: 69;
Date: 2005;
Original page

Keywords: Vax-SPIRAL | leptospirosis | diafiltración | Vax-SPIRAL | leptospirosis | diafiltration

ABSTRACT
Se propuso sustituir la tecnología actual de la operación de lavado por un sistema de microfiltración tangencial en las etapas de lavado del cultivo de Leptospira interrogans canicola canicola. Se demostró que es aplicable este sistema porque no hubo afectación celular y se obtuvieron altos niveles de eliminación de contaminantes.It was proposed to substitute the present technology of the lavage operation for a tangential microfiltration system at the lavage stages of the culture of Leptospira interrogans canicola canicola. It was proved that this system may be applied, since no cellular affectation was observed and high pollutant elimination levels were obtained.
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