Academic Journals Database
Disseminating quality controlled scientific knowledge

ESTIMATION OF RECURRENCE RISK AND GENETIC COUNSELLING OF FAMILIES WITH EVIDENCE OF ISOLATED (UNSYNDROMIC) CLEFT LIP AND PALATE IN SUCEAVA COUNTY, ROMANIA

ADD TO MY LIST
 
Author(s): Crsitian Tudose | Cristina Lacatusu | Iuliana Csilla Bara | Mihaela Tudose | Ioan Bara

Journal: Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
ISSN 1582-3571

Volume: 8;
Issue: 2;
Date: 2007;
Original page

ABSTRACT
: Cleft lip and/or palate are the most frequent facial congenital malformations and represent a dramatic situation at birth, which involves important functional, aesthetic, psychological and social impairment that motivates the necessity of a thorough genetic study in the view of genetic counselling. We have studied the families of 100 children with clefts born during the years 1985-1996 in Suceava county and selected from the evidences of the Children Hospital Suceava. The recurrence risk was determined in accordance with the rules of calculation for multifactorial inheritance; it varied between 2 – 5% for the majority of cases (77%) which corresponds to a small risk degree; only in 23% of cases the risk varied between 6 – 15% which corresponds to a medium risk degree

Tango Rapperswil
Tango Rapperswil

     Save time & money - Smart Internet Solutions