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EVALUATION OF ANTI-HIV-1 ACTIVITY FROM CESTRUM NOCTURNUM AERIAL PARTS AND PHYTOCHEMICAL ANALYSIS

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Author(s): KHALED RASHED | XING-JIE ZHANG | MENG-TING LUO | YONG-TANG ZHENG

Journal: Reviews of Progress
ISSN 2321-3485

Volume: 1;
Issue: 5;
Start page: 12;
Date: 2013;
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Keywords: Cestrum nocturnum | aerial parts | cytotoxicity | anti-HIV-1 activity | Phytoconstituents

ABSTRACT
This study deals with evaluation of HIV-1 activity from Cestrum nocturnum aerial partsextracts and investigation of phytoconstituents in the plant extracts. Different extracts fromCestrum nocturnum aerial parts, methanol 80%, ethyl acetate, butanol and aqueous extracts weretested for their anti-HIV-1 activity using the syncytia formation assay. All the extracts wereweak active as anti-HIV-1 agents. Phytochemical analysis of Cestrum nocturnum extracts haveshown the presence of different phytocomponents, saponins, triterpenes and/or sterolsflavonoids, tannins and coumarins. The results confirm that all extracts from Cestrum nocturnumaerial parts have a weak anti-HIV-1 activity.
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