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EVALUATION OF ANTI HIV-1 ACTIVITY FROM CESTRUM NOCTURNUM AERIAL PARTS AND PHYTOCHEMICALANALYSIS

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Author(s): KHALED RASHED | XING-JIE ZHANG | MENG-TING LUO | YONG-TANG ZHENG

Journal: Reviews of Progress
ISSN 2321-3485

Volume: 1;
Issue: 8;
Start page: 1;
Date: 2013;
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Keywords: Cestrum nocturnum | aerial parts | cytotoxicity | anti-HIV-1 activity | Phytoconstituents.

ABSTRACT
This study deals with evaluation of HIV-1 activity from Cestrum nocturnum aerial parts extracts and investigation of phytoconstituents in the plant extracts. Different extracts from Cestrum nocturnum aerial parts, methanol 80%, ethyl acetate, butanol and aqueous extracts were tested for their anti-HIV-1 activity using the syncytia formation assay. All the extracts were weak active as anti-HIV-1 agents. Cestrum nocturnum aerial parts extracts contained saponins, triterpenes and/or sterols flavonoids, tannins and coumarins. The extracts from Cestrum nocturnum aerial parts showed a mild anti-HIV-1 activity.
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