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Evaluation indices of hepatitis-related hepatic cirrhosis and their relations to postoperative awakening time

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Author(s): C. Xuexin | M. Hanxiang | X. Lize | M. Jinhai | L. Hong

Journal: Medical Journal of the Islamic Republic of Iran
ISSN 1016-1430

Volume: 21;
Issue: 2;
Start page: 97;
Date: 2007;
Original page

Keywords: hepatic cirrhosis | awakening time | CTP scoring | MELD scoring | Prealbumin | portal venous pressure; total intravenous anesthesia

ABSTRACT
 Abstract Objective: To investigate the anesthesia-postoperative awakening time (AT) of hepatitis- related cirrhosis patients and their relations to grading scores, portal venous pressure (PVP), prealbumin (PA), and age, to predict postoperative AT and provide a basis for adjustment of anesthetic doses during operation. Methods: Atotal of 71 patients with hepatic cirrhosis and hypersplenism at ASAgrade I to II were subject to splenectomy and gastric cardia devascularization under total intravenous anesthesia. The depth control of anesthesia (MAP±20% base value; BIS40-60) and the monitoring of muscular relaxation were taken by HXD-I multifunctional quantitative electroencephalogram monitor. Child-Turcotte-Pugh (CPT) and Model for endstage liver disease (MELD) scoring were carried out prior to operation so that intraoperative PAand PVP as well as postoperative extubation time (ET) and AT were determined. Results: Both ET and postoperative recovery time of the cirrhosis group were significantly longer than those of the non-cirrhosis group (P
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