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EVALUATION OF NIMBA TAILA AND MANJISTHA CHURNA IN NON HEALING ULCER

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Author(s): Singh Anil Kumar | Srivastava Prabhat Kumar | Shukla Vijay Kumar

Journal: International Research Journal of Pharmacy
ISSN 2230-8407

Volume: 2;
Issue: 5;
Start page: 201;
Date: 2011;
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Keywords: Nimba (Azadirachta indica A. Juss.) | Manjistha (Rubia cordifolia Linn.) | Non healing ulcer (Dushta vrana) | Taila (oil) | Churna (powder) | Kwatha (decoction)

ABSTRACT
This clinical study was done in fifty-one cases of non-healing ulcers of more than six weeks duration to evaluate the efficacy of Nimba taila (Neem oil) externally and Manjistha churna (powder) orally as well as its kwatha externally with an aim to provide an effective management in cases of non healing ulcers. For assessment, wound measurement was done before, during and after treatment and wound healing time as well as lab tests like swab culture, X-ray of affected part, Hemoglobin, Total Leucocytes Count, Differential Leucocytes Count, Liver Function Test, blood sugar level and HbA1c were recorded. Patients with tubercular, malignant ulcers and with ulcers of less than 6 weeks duration were excluded from the study. In the patients treated with only Nimba taila, 31.2% (5/16) patients had 50% healing at eight weeks therapy while with only Manjistha churna, 20.0% (3/15) patients had 50% healing at eight weeks therapy but in the cases, treated with both the drugs, 75.0% (15/20) patients had achieved 50% healing at eight weeks therapy. The study suggests that there is an added effect (quick healing of wound) of Nimba taila with Manjistha churna & its kwatha in cases of non healing diabetic ulcer and single use of Nimba taila or Manjistha churna is not much significant but it is observed keenly that use of Nimba taila alone is comparatively more beneficial than single use of Manjistha churna. It means that both the drugs together are more effective than their separate use.
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