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Evaluation of oxidative status in iron deficiency anemia through total antioxidant capacity measured using an automated method

Author(s): Mehmet Aslan | Mehmet Horoz | Hakim Çelik

Journal: Turkish Journal of Hematology
ISSN 1300-7777

Volume: 28;
Issue: 01;
Start page: 42;
Date: 2011;
Original page

Keywords: Iron deficiency anemia | total peroxide | total antioxidant capacity | oxidative stress

Objective: Oxidative stress, an increase in oxidants and/or a decrease in antioxidant capacity, is one of the potential biochemical mechanisms involved in the pathogenesis of iron deficiency anemia. The objective of this study was to evaluate the oxidative status and to determine whether there is any relationship between oxidative status and the severity of anemia in patients with iron deficiency anemia using an automated method.Materials and Methods: Twenty-six subjects with iron deficiency anemia and 20 healthy controls were enrolled in the present study. Serum total antioxidant capacity, serum total peroxide level and oxidative stress index were determined in all study subjects.Results: Serum total antioxidant capacity was significantly lower in patients with iron deficiency anemia than controls (p

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