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Evaluation of Peripheral Blood Smear for Myelodysplasia in Breast Cancer Patients who Received Adjuvant Antracycline

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Author(s): Hasan Mutlu | Zeki Akca | Havva Uskudar Teke | Hediye Ugur

Journal: Eurasian Journal of Medicine
ISSN 1308-8734

Volume: 43;
Issue: 03;
Start page: 173;
Date: 2011;
Original page

Keywords: Anthracycline | Breast cancer | Chemotherapy side effect | Leukemia | Myelodysplasia

ABSTRACT
Objective: Therapy-related myeloid neoplasms (t-MN) account for approximately 10% to 20% of all cases of AML (acute myeloid leukemia), MDS (myelodysplastic syndrome) and MDS/MPN (myelodysplastic syndrome/myeloproliferative neoplasms), MDS, and MDS/MPN. In our study, we evaluated peripheral blood smear samples and hemogram values in breast cancer patients who were receiving adjuvant anthracycline regimens and were in remission. Materials and Methods: A total of 78 patients receiving anthracycline-based adjuvant chemotherapy treatment from Kayseri Research and Training Hospital and Mersin State Hospital were enrolled in the study. Their adjuvant treatments had been completed at least 18 months prior to the study. Results: Two patients complained of anemia (2.2%) (Hb
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