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Evaluation of Possible Interactive Factors with Thyrotropin Level in Screening Program of Congenital Hypothyroidism in Ahvaz

Author(s): Aminzadeh M | Chomeili B | Aramesh MR | Ghorbani R

Journal: Scientific Medical Journal
ISSN 1026-8960

Volume: 9;
Issue: 6;
Start page: 553;
Date: 2011;
Original page

Keywords: Congenital hypothyroidism | Screening | Thyrotropin | Ahvaz

Background and Objective: Accuracy and efficiency in screening program for congenital hypothyroidism (CH) in each geographical area requires regional studies and updating protocols. This study performed to assess factors possibly interactive with the result of screening test for CH in Ahvaz. Subjects and Methods: During 19 months (Nov 2006-May 2008) all newborns in Ahvaz enrolled in screening by heel prick sampling for TSH then were referred for confirmation if it was ≥5mIU/L. In next step, second assays considered as hypothyroid if TSH remained ≥10 mIU/L. The factors were studied including: age, history of hypothyroidism in mother, sex, birth weight (BW), birth number, feeding, parental consanguinity, TSH levels and duration of normalization of TSH.Results: In totally of 35655 neonates were screened. 1162 cases (55.8%M,44.2% F with p
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