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"Evaluation of in vitro antimicrobial drug-resistance in Imam Khomini hospital "

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Author(s): Hajizade N | Daneshjo Kh

Journal: Iranian Journal of Pediatrics
ISSN 2008-2142

Volume: 13;
Issue: 2;
Start page: 133;
Date: 2003;
Original page

Keywords: rug-resistance | antibiotic | organisms | antibiogram

ABSTRACT
Since 1950 with the extensive use of antibiotics in medicine and agriculture industries, resistant organisms are growing. The rapid evolution of resistance has limited the duration of the effectiveness of specific agents against certain pathogens. It urges us to expand our knowledge of antibiotic resistance of different organisms in order to maximize continued efficacy of the antibiotic. Usage of appropriate antibiotic in every region depends on the results of antibiotic resistance of organisms in that region. In this article the results of 320 cases of positive culture and their antibiogram , from children admitted to pediatric and neonatal ward in Imam Khomeini hospital in 1381 is reported. Commonest organisms in blood culture were Staphylococcus epidermidis(25%), in CSF: Staphylococcus Aureus (30%) and Staphylococcus epidermidis (30%), in urine: E.coli (60%) and in secretions Staphylococcus aureus (35%). Unfortunately because of irrational antibiotic usage, resistance to ampicillin (60-95%) and co-trimoxazole (55-100%) was very high. Also resistance to some other antibiotics was high.
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