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Ex-Utero intrapartum procedure for congenital high airway obstruction syndrome in a neonate: First case in Alexandria

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Author(s): Youssef Mohammed

Journal: Journal of Indian Association of Pediatric Surgeons
ISSN 0971-9261

Volume: 12;
Issue: 4;
Start page: 226;
Date: 2007;
Original page

Keywords: CHAO syndrome | Ex utero intrapartum treatment | oropharyngeal teratoma

ABSTRACT
Introduction: Large fetal neck masses can present a major challenge for securing an airway at birth with associated risks of hypoxia, brain injury and death. Teratomas of the oropharynx are rare, presenting 3% of teratomas in childhood, and are treated by surgical excision. If respiratory distress accompanies the lesion, priority must be given to the securing of the airway. Case History: We present a case of an infant who was diagnosed antenatally as having a huge oropharyngeal teratoma. The anaesthetic, surgical and neonatology teams were ready to perform surgical excision depending on the placental circulation immediately after securing the airway. The tumour weighed 1591 g and was 20 x 22 x 12 cm. The patient was a male and weighed 715 g. Histopathology showed Grade II teratoma. Conclusion: Large fetal neck masses can present a major challenge for securing an airway at birth with associated risks of hypoxia, brain injury and death. A multidisciplinary team approach combined with an accurate prenatal diagnosis obtained through fetal ultrasound is the key to a successful outcome. Ex utero intrapartum treatment (EXIT) that is based on the placental blood during intubation, tracheostomy or surgical excision is the standard procedure.
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