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Exchange for strategies in the alternative methods to evaluate the potential of the ocular irritating effect

Author(s): Luis Alfredo Rosario Fernández | Daniel Francisco Arencibia Arrebola

Journal: RETEL : Revista de Toxicología en Línea
ISSN 1668-091X

Volume: 25;
Start page: 1;
Date: 2009;
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Keywords: Ocular irritating effect | Draize test | alternative methods | isolated eye assay

From the 90 years have been carried out several studies of alternative in vitro validation to the ocular irritation assays. At the present time, has been refined the method to reduce the animals suffering, validating several alternatives in vitro with regulators finals to identify severe irritating products. These procedures have even this way some limitations. In this short communication we will try to carry out a bring up to date on the in vitro methods of the ocular irritation assays and inside these the more used in our days the isolated eye assay. We utilized this way to propitiate an exchange as for strategies in this evaluations topic among the journal readers.
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