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Expression of steroidogenic enzymes in porcine polycystic ovaries.

Author(s): Anna Kozłowska | Mariusz Majewski | Barbara Jana

Journal: Folia Histochemica et Cytobiologica
ISSN 0239-8508

Volume: 47;
Issue: 2;
Start page: 257;
Date: 2009;
Original page

In the present study the expression pattern of the cholesterol side-chain cleavage cytochrome (P450(scc)), 3beta-hydroxysteroid dehydrogenase (3beta-HSD) and aromatase (P450(arom)) was analyzed in the health and polycystic ovaries of gilts by means of the Western blot and immunohistochemistry. The polycystic status of ovaries was induced by i.m. dexamethasone (DXM) injections on days 7-21 of the estrous cycle. Macroscopic observation of ovaries of DXM-treated gilts revealed the presence of cysts (1-2 cm in diameter, with a mean number of 7.0+/-1.2 per ovary), a decrease (P
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