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F18-FDG Heart uptake in oncologic PET studies.

Author(s): González, Patricio, | Massardo, Teresa. | Alavi, Abass.

Journal: Alasbimn Journal
ISSN 0717-4055

Volume: 3;
Issue: 11;
Date: 2001;
Original page

Keywords: F-18 FDG | Standardized Uptake Values | PET studies.

Background: PET scanning with F-18 FDG is a useful technique to detect malignant lesions. The goal of this work to analyze the frequency of increased heart uptake in routine PET oncologic studies and to correlate F-18 FDG Standardized Uptake Values (SUV) to blood glucose level (BGL).Material: We analyzed data from 31 patients referred for whole body scans. There were 15 females and 16 males, whose mean age was 60 years (range: 24-85).Method: Before the test, patients were asked to fast for at least 4 h. Mean F-18 FDG dose injected intravenously was 9.8 mCi (range: 5.8-18.4). PET acquisition was performed using the UGM PENN PET 240H Camera. A transmission scan was acquired with Cs-137; the emission scan was obtained 40-50 min. after injection. After reconstruction and correction for decay, scatter and attenuation, images were interpreted visually: No heart activity = Grade 0; Mild uptake = Grade 1; Moderate uptake = Grade 2; and Marked uptake = Grade 3. SUV heart and liver were calculated in all cases.Results: Thirteen patients were rated as Grade 3 (42%), 5 as Grade 2 (16%), 4 as Grade 1 (13%) and 9 as Grade 0 (29%). Mean heart SUV was 4.5± 2.7 (range: 0.5-10.8). Correlation data between heart SUV and BGL showed a very low r coefficient value (0.14). The mean value of BGL in 13 patients with heart uptake scored Grade 3 was 102.9 mg/dl and that of 9 cases scored as Grade 0 was 112.8 (NS). The mean SUV in the liver of 30 patients was 1.6 ± 0.5, ranging from 0.8 to 2.8 (p

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