Academic Journals Database
Disseminating quality controlled scientific knowledge

Factors Affecting the Efficacy of Pramipexole in Patients with Restless Legs Syndrome

Author(s): Mohammad Rezvani | Babak Zamani | Seyed-Mohammad Fereshtehnejad

Journal: Acta Medica Iranica
ISSN 0044-6025

Volume: 51;
Issue: 6;
Start page: 377;
Date: 2013;
Original page

Keywords: Efficacy | Pramipexole | Restless Legs Syndrome (RLS) | Treatment

Dopamine agonists, particularly nonergot dopamine agonists such as pramipexole, have become the mainstay of therapy for patients with symptoms of restless legs syndrome (RLS). This study was designed to evaluate the factors affecting the efficacy of pramipexole in patients with RLS. Fifty-nine eligible RLS patients referred to neurology clinic of Rasoul-e-Akram Hospital (Tehran, Iran) were recruited in this study. All of the patients received an oral dose of 0.18 mg pramipexole. The severity of RLS symptoms were evaluated including sleep disorder, symptomatic days per week and symptomatic hours per day, both at the beginning and at the end of follow-up time. Different baseline and follow-up variables were also recorded and their relationships with the outcomes were assessed. The mean severity values of different symptoms significantly decreased after treatment with pramipexole (P
Why do you need a reservation system?      Affiliate Program