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FAST DISSOLVING DRUG DELIVERY SYSTEM - A REVIEW

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Author(s): Sharma Ritika | Rajput Meenu | Prakash Pawan | Sharma Saurabh

Journal: International Research Journal of Pharmacy
ISSN 2230-8407

Volume: 2;
Issue: 11;
Start page: 21;
Date: 2011;
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Keywords: Fast dissolving drug delivery system | Super‚ÄźDisintegrants | Conventional techniques | Patented technology | Excipients used in FDDTs | Evaluation of FDDTs.

ABSTRACT
Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however in many cases immediate onset of action is required than conventional therapy. To overcome these drawbacks, immediate release pharmaceutical dosage form has emerged as alternative oral dosage forms. There are novel types of dosage forms that act very quickly after administration. Drug delivery systems are becoming sophisticated day by day as pharmaceutical scientists has acquired a better understanding of the physicochemical and biochemical parameters of drugs and excipients. Over the past three decades, fast disintegrating tablets (FDTs) have gained considerable attention and is one of the most widely employed commercial product which is preferred alternative to conventional tablets and capsules especially for the pediatric and geriatric patients and for the patients who are bedridden, those having hand tremors, motion sickness, disphagia and who may not have access to water during traveling or who are uncooperative, on reduced liquid intake plan and also preferred in sudden episodes of allergic attack. Fast-dissolving drug delivery systems may offer a solution for these problems.
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