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Fibrinolytic activity in human malignant tumors.

Author(s): Sarode R | Marwaha N | Gupta N

Journal: Indian Journal of Cancer
ISSN 0019-509X

Volume: 28;
Issue: 4;
Start page: 181;
Date: 1991;

Keywords: Adenocarcinoma | physiopathology | Breast Neoplasms | physiopathology | Carcinoma | Intraductal | Noninfiltrating | physiopathology | Comparative Study | Female | Fibrinolysis | Gastrointestinal Ne

We have studied fibrinolytic activity of 12 cases of infiltrating duct carcinoma of breast (7 metastatic and 5 non-metastatic) and ten cases of adenocarcinoma of gastrointestinal tract (5 each of metastatic and nonmetastatic), and compared with some of their normal tissue counterparts. Both metastatic and non-metastatic tumors of breast and gastrointestinal tract had significantly higher levels of fibrinolytic activity as compared to normal tissues. Though mean fibrinolytic activity (expressed as ug/ml of urokinase activity) of metastatic tumors of breast and gut had higher values as compared to non-metastatic counterparts, however it did not reach statistical significance.
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