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Flow Rate through a Blood Vessel Deformed Due To a Uniform Pressure

Author(s): Amy Cypher | J Mohamed B. Elgindi | Hatem Kouriachi | David Peschman | Reba Shotwell

Journal: Journal of Biomaterials and Nanobiotechnology
ISSN 2158-7027

Volume: 02;
Issue: 04;
Start page: 369;
Date: 2011;
Original page

Keywords: Blood Vessel | Deformation of Elastic Tube

In this paper, we present the mathematical equations that govern the deformation of an imbedded blood vessel under external uniform pressure taking into consideration the nonliner behavior of the soft tissue surrounding the vessel. We present a bifurcation analysis and give explicit formulas for the bifurcation points and the corresponding first order approximations for theemph{non-trivial} solutions. We then show the results of a MATLAB program that integrates the equilibrium equations and calculates the blood flow rate through a deformed cross section for given values of the elasticity parameters and pressure. Finally, we provide (numerical) verification that the flow rate as a function of the elasticity parameters of the soft tissue surrounding the blood vessel is convex, and therefore validate the invertibility of our model.
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