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Flucytosine for treatment of Candida albicans in H1N1-positive patient

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Author(s): Samra Tanvir | Yadav Amlendu | Banerjee Neerja | Pawar Mridula | Deepak Desh

Journal: Indian Journal of Pharmacology
ISSN 0253-7613

Volume: 42;
Issue: 5;
Start page: 318;
Date: 2010;
Original page

Keywords: Flucytosine | empyema thoracis | Candida albicans | H1N1 infection

ABSTRACT
A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida species sensitive to flucytosine but resistant to amphotericin B and azole group of antifungals. Monotherapy with flucytosine led to clinical and radiological improvement.
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