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Formulation and Evaluation of Mouth Dissolving Tablets Sildenafil Citrate

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Author(s): Kumar S | Sachdeva M | Bajpai M.

Journal: Journal of Pharmaceutical Science and Technology
ISSN 0975-5772

Volume: 2;
Issue: 4;
Start page: 202;
Date: 2010;
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Keywords: Mouth dissolving | Fast disintegrating | Direct compression

ABSTRACT
Methods to improve patient’s compliance have always attracted scientist towards the development of fancy oral drug delivery systems. Among them, mouth dissolving drug delivery systems (MDTs) have acquired an important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life. MDTs have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact with saliva, thus obviating the requirement of water during administration. Therefore, these dosage forms have lured the market for a certain section of the patient population which include dysphagic, bed ridden, psychic, geriatric and patients. Several techniques have been developed in the recent past, to improve thedisintegration quality of these delicate dosage forms without affecting the integrity..

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