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From HOPE trial to ONTARGET trial: the «hope» to reach the «target» — to improve prognosis in high risk patients

Author(s): Yu.M. Lopatin

Journal: Racionalʹnaâ Farmakoterapiâ v Kardiologii
ISSN 1819-6446

Volume: 2;
Issue: 4;
Start page: 47;
Date: 2006;
Original page

Keywords: high cardio-vascular risk | ramipril | telmisartan | НОРЕ trial | ONTARGET trial

Results of HOPE trial are analyzed. It is noted, that treatment with angiotensine converting enzyme inhibitor (iACE) ramipril improves the prognosis in high risk cardio-vascular patients. The objectives and study design of ONTARGET/TRANSCEND trials are introduced. Perspectives of joint use of ACE inhibitor and antagonist of angiotensin II receptor are discussed.
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