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FSH Injections and Ultrasonography Determine Presence of Ovarian Components in the Evaluation of Ovotesticular Disorders of Sex Development

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Author(s): Shannon French | Luisa Rodriguez | Alan Schlesinger | Laurence McCullough | Jennifer Dietrich | John Hicks | Lefkothea Karaviti

Journal: International Journal of Pediatric Endocrinology
ISSN 1687-9848

Volume: 2009;
Date: 2009;
Original page

ABSTRACT
Three infants with ambiguous genitalia and suspected ovotestes were given recombinant FSH to induce ovarian follicular development. The development of follicles in the gonadal tissue suggested the presence of ovarian tissue in two of the three infants. This method may provide a means to better characterize gonadal anatomy in patients affected by disorders of sex development (DSD). Sonographic information poststimulation provided parents with earlier and more specific education and support concerning the possible need for confirmative gonadal biopsy treatment options.
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