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Fu Zi Prevent Extreme Cold Stress in Broilers Through Anti-Oxidative Activity

Author(s): X.Y. Chen | S.H. Jing | R.S. Jiang | Z.Y. Geng

Journal: Journal of Animal and Veterinary Advances
ISSN 1680-5593

Volume: 11;
Issue: 6;
Start page: 849;
Date: 2012;
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Keywords: Radix aconiti laterlis preparata | nitric oxide | extreme cold stress

Radix aconiti laterlis preparata (Fu Zi in Chinese), a Chinese traditional medicine has been widely used for Yang deficiency. Recent clinical studies have shown that Fu Zi could ameliorate stressed condition but the mechanisms underlying the anti-stress effect of Fu Zi remains unknown. In this study, researchers examined the effects of Fu Zi on the treatment of broilers exposed to Extreme Cold Stress (ECS). The levels of Nitric Oxide (NO) and creatine kinase in plasma were measured and Hsp70 mRNA expression in different tissues was analyzed. Broilers subjected to ECS exhibited increased NO content before 3 h and increased Hsp70 expression under a time and tissue-dependent manner. Biochemically, Fu Zi reversed ECS-induced increases in NO and Hsp70 mRNA and the results suggest that Fu Zi supplemented broilers kept an elevated plasma NO content through anti-oxidative activity during ECS.
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