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Fungal infections in the immunocompromised host

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Author(s): Wanke Bodo | Lazéra Márcia dos Santos | Nucci Marcio

Journal: Memórias do Instituto Oswaldo Cruz
ISSN 0074-0276

Volume: 95;
Issue: suppl.1;
Start page: 153;
Date: 2000;
Original page

Keywords: fungal infections | immunocompromised host | risk factors | candidiasis and aspergillosis

ABSTRACT
In recent years many remarkable changes occurred in our way of life, producing opportunities for microbes. All these changes are related to the recent emergence of previously unrecognized diseases, or the resurgence of diseases that, at least in developed countries, were thought to be under control. This concept is reviewed regarding fungal infections and their agents in the immunocompromised host. The changing pattern of these infections, the portals of entry of fungi into the human host, fungal pathogenicity and the main predisposing factors are analyzed. Opportunistic fungal infections in cancer, organ transplant and acquired immunodeficiency syndrome patients are reviewed, specially candidiasis and aspergillosis.
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