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Granulosis rubra nasi: a rare condition treated successfully with topical tacrolimus

Author(s): Piyush Kumar | Anubhav Gosai | Ashim Kumar Mondal | Niharika Ranjan Lal | Ramesh Chandra Gharami

Journal: Dermatology Reports
ISSN 2036-7392

Volume: 4;
Issue: 1;
Start page: e5;
Date: 2012;
Original page

Keywords: Granulosis rubra nasi | GRN | eccrine sweat glands | face | hyperhidrosis

A 20 years-old girl presented with multiple asymptomatic reddish vesicles on face for four years. It used to get worse in summer and was associated with localized hyperhidrosis. The lesions were notable for disappearance on diascopy. Histopathology from the vesicle showed mononuclear cell infiltration in the upper dermis, especially around eccrine sweat apparatus, along with dilatation of superficial capillaries and lymphatics. Based on clinical presentation and histopathology, diagnosis of Granulosis rubra nasi (GRN) was made. GRN usually resolves at puberty; however, rarely it may persist in adulthood. We here report a case of GRN having lesions in adulthood. Moreover, she showed excellent response to topical tacrolimus, a finding not observed in literature.
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