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Health-Related Quality of Life in Primary Immune Deficient Patients

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Author(s): Habibeh Mozaffari | Zahra Pourpak | Sara Pourseyed | Mostafa Moin | Abolhassan Farhoodi | Asghar Aghamohammadi | Masoud Movahedi | Mohammad Gharagozlou | Neda Entezari

Journal: Iranian Journal Of Allergy, Asthma and Immunology
ISSN 1735-1502

Volume: 5;
Issue: 1;
Start page: 23;
Date: 2006;
Original page

Keywords: Immunologic Deficiency Syndromes | Pediatrics | Quality of Life | Questionnaire

ABSTRACT
The primary immunodeficiency (PI) disorders are abnormalities in development and maturation of the immune system. Individuals with PI disease may experience frequent infections, which limit their abilities to exhibit physical and psychological well-being secondary to their illness. In this survey we compared health-related quality of life of primary immune deficient patients with healthy children. The case-control study was designed for patients with PI disease who were referred to Children Medical Center in 2004-2005. Demographic information was taken and Pediatric Quality Of Life (PEDQOL) questionnaire were filled for 50 PI patients and 100 healthy children. The mean age in PI patients was 12.62± 3.65 (range from 8 to 18) years and in the control group was 11.04± 3.3 years. In PI patients 68% were male and 32% female .Most patients with PI disease had a diagnosis of common variable immunodeficiency (54%) or X-linked agammaglobulinemia (24%). Patients with PI disease had great limitations in physical functioning and psychological well-being (p
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