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Health-Related Quality of Life in Primary Antibody Deficiency

Author(s): Asghar Aghamohammadi | Ali Montazeri | Hassan Abolhassani | Sepideh Saroukhani | Sarvenaz Pourjabbar | Mahmoud Tavassoli | Behzad Darabi | Amir Imanzadeh | Nima Parvaneh | Nima Rezaei

Journal: Iranian Journal Of Allergy, Asthma and Immunology
ISSN 1735-1502

Volume: 10;
Issue: 1;
Start page: 47;
Date: 2011;
Original page

Keywords: Common Variable Immunodeficiency | Primary Antibody Deficiency | Quality of Life

Patients with primary antibody deficiencies (PAD) are susceptible to recurrent and chronic infections and a variety of complications. This study was performed to assess quality of life (QoL) of PAD patients who were under long term treatment and regular follow-up.Thirty six adults with proved diagnosis of PAD, who had received regular intravenous immunoglobulin replacement therapy, were enrolled in this study. The QoL of selected PAD patients was measured by Medical Outcomes Study 36-item Short-Form (SF-36) Health Survey questionnaire.The patients with PAD showed significantly reduced scores in physical component in comparison with healthy age-sex matched control subjects (60.2±20.1 vs. 85.5±4.7, P

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