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Hematobiochemical changes of lead Poisoning and amelioration with Ocimum sanctum in wistar albino rats

Author(s): Sujatha K. Karamala | Sri latha ch | Anjaneyulu Y. | Chandra Sekhara Rao T.S. | Sreeni Vasulu D and Amravathi P. Pidugu

Journal: Veterinary World
ISSN 0972-8988

Volume: 4;
Issue: 6.000;
Start page: 260;
Date: 2011;
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Keywords: Lead poisoning | hematobiochemical alterations | Ocimum amelioration | wistar rats

An experiment was carried out to study the hematobiochemical changes of chronic lead poisoning in adult male wistar albino rats for a period of twelve weeks. Adult 216 healthy rats were randomly divided into six groups viz. control (groupI), higher dose of lead acetate @60mgs/kg bwt (group II), Lower dose of lead acetate @ 30 mgs / kg bwt (group III), Higher dose of lead + Ocimum @ 400 mgs/ kg bwt (group IV), lower dose of lead + Ocimum @ 400 mgs/ kg bwt (group V), Ocimum control (group VI). All lead treated and ameliorated groups given Lead acetate/ lead + Ocimum orally for three days in a week for a period of twelve weeks. The mean PCV, Hb, values were reduced significantly (P
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