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High-grade primary pulmonary leiomyosarcoma

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Author(s): Rodrigo Afonso da Silva Sardenberg | Renato Cangnaci Neto | Fernanda Cavalcanti | Riad Naim Younes

Journal: Einstein
ISSN 1679-4508

Volume: 9;
Issue: 4;
Start page: 523;
Date: 2011;
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Keywords: Leiomyosarcoma | Lung neoplasms | Sarcoma | Case reports

ABSTRACT
Primary sarcomas of the lung are rare and account for 0.5% of all primary lung tumors. There were approximately 300 cases described in the literature as of 2006. All histologic types of sarcoma were described, and the most common intrathoracic types reported were angiosarcoma, leiomyosarcoma, fibrosarcoma, hemangiopericytoma, and rhabdomyosarcoma. The biological behavior of these tumors is not well-known due to their low frequency. Leiomyosarcomas represent one of the most common subtypes encountered in the lungs, and usually occur during the sixth decade, with male predominance. Although the frequency of metastatic disease is not related to tumor size, prognosis was reported to be poorer in high-grade tumors. In comparison with other sarcomas, survival after complete resection of pulmonary leiomyosarcoma was reported as longer. We report on a patient with primary leiomyosarcoma originating from the bronchus with complete resection and long-term follow-up.
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