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High grade lymphoma in the nasopharynx presented as sudden onset of bilateral blindness

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Author(s): Shambhu S | Vose M

Journal: BMC Ophthalmology
ISSN 1471-2415

Volume: 4;
Issue: 1;
Start page: 2;
Date: 2004;
Original page

Keywords: lymphoma | nasopharynx | blindness

ABSTRACT
Abstract Background Sudden onset of bilateral blindness is rare; hysteria, cortical infarction or bilateral central retinal arterial occlusion can cause this. Case presentation The authors describe a single case of sudden onset bilateral blindness in a patient with nasopharyngeal carcinoma, which is unusual. Biopsy revealed a high-grade lymphoma. After treatment the patient made a complete visual recovery, with no evidence of visual sequelae and no clear reasons for this complete recovery. Conclusion CT and MR imaging did not demonstrate any lesions invading any part of the visual pathway or even indeed the occipital cortex. High dose steroids may have reduced the mass effect of the tumour or the blindness may have been hysterical but is unlikely.
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