Academic Journals Database
Disseminating quality controlled scientific knowledge

Histopathological Safety Evaluation of Newly-Developed MgO Sealer

ADD TO MY LIST
 
Author(s): Nakano K | Tomida M | Sato M | Matsuura S | Yamamoto A | Kasahara E | Kawakami T

Journal: European Journal of Medical Research
ISSN 2047-783X

Volume: 16;
Issue: 12;
Start page: 526;
Date: 2011;
Original page

Keywords: tissue reaction | histopathological evaluation | root canal sealer | magnesium oxide

ABSTRACT
Abstract We aimed to evaluate the subcutaneous tissue reaction to a newly-developed MgO Sealer for root canals. We injected the experimental material and three existing control materials into the dorsal area of 43 male ddY mice. One week and 12 weeks after embedding, the tissue surrounding the embedding sites was removed and histopathological examination was performed. The results demonstrate that the basic histopathological reaction is the formation of fibrous capsules consisting of granulation tissue around the experimental and control embedded materials. Based on our results, we believe that the newly-developed MgO Sealer is as safe as the existing control materials and can be considered for dental use as a root canal sealer.
Affiliate Program      Why do you need a reservation system?