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Hyoscine-N-butylbromide Versus Atropine as Labour Accelerant and Analgesic: A Randomized Clinical Trial

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Author(s): Zahra Fardiazar | Fatemeh Niknami | Simin Mashayekhi | Morteza Ghojazadeh

Journal: Pakistan Journal of Biological Sciences
ISSN 1028-8880

Volume: 16;
Issue: 9;
Start page: 443;
Date: 2013;
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Keywords: Labor | labor induction | hyoscine | analgesic | pregnancy

ABSTRACT
The aim of this study was to compare the efficacy of atropine and hyoscine-N-butyl bromide in reducing the pain and time length of the first stage of labour. In a single blind randomized clinical trial, 120 term pregnancies were enrolled from July 2009 to March 2011. A parallel design was used to randomly assign subjects into two equal groups including 60 participants in each group. Hyoscine-N-butylbromide was administered 40 mg intravenously in the first group and intravenous atropine was given in second group at a dose of 0.5 mg. The participants of the two trial arms were similar according to the distribution of background variables. The pain trend through the study follow up was found to be different between groups (p
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