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Identification of Marker Protein, In Patient with Chronic Liver Disease

Author(s): Fauzia Tabassum | Rukhshan Khurshid | M. Waheed Akhtar

Journal: Pakistan Journal of Biological Sciences
ISSN 1028-8880

Volume: 3;
Issue: 9;
Start page: 1509;
Date: 2000;
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Keywords: chronic liver disease | protein and electrophoresis

Hepatitis C virus causes acute and chronic hepatitis. It has a high propensity for transition to chronicity. In some cases over 50% patients developed chronic hepatitis. We have undertaken studies on protein/ enzyme of serum of both normal and patient with chronic liver disease. Serum was analysed enzymatically and electrophoretically using reducing and non-reducing condition. It is observed that a protein of 14 Kda may be missing or in trace amount in serum of patients with chronic liver disease. Therefore it may be possible that this may be a cause of chronic liver disease. Further research is in progress for identification and characterization of missing protein.
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