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Immunocompromised host: from the early events until the impact of acquired immunodeficiency syndrome

Author(s): Costa Sylvio Celso Gonçalves da

Journal: Memórias do Instituto Oswaldo Cruz
ISSN 0074-0276

Volume: 95;
Issue: suppl.1;
Start page: 141;
Date: 2000;
Original page

Keywords: immunocompromised host | acquired immunodeficiency syndrome-Aids | human immunodeficiency virus-HIV

The concept that microorganisms can modulate the host resistance was historically reviewed in the present article. The importance of African trypanosomiasis in the development of the research on immunosuppression as well as the impact of human immunodeficiency virus infection are discussed. Each day new opportunistic organisms establish a constant challenge for the correct diagnosis of concomitant infections in acquired immunodeficiency syndrome. The importance of parasite infection in the balance of host resistance in the third world was emphasized. Finally, some aspects of Leishmania as opportunistic organisms were presented.
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