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Immunohistochemical expression of androgen receptor and prostate-specific antigen in breast cancer.

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Author(s): Diana Narita | Marius Raica | Cristian Suciu | Anca CĂŽmpean | Andrei Anghel

Journal: Folia Histochemica et Cytobiologica
ISSN 0239-8508

Volume: 44;
Issue: 3;
Start page: 165;
Date: 2006;
Original page

ABSTRACT
AR (androgen receptor) and PSA (prostate-specific antigen) are involved in the pathogenesis of breast cancer, but their role is not clearly defined. The purpose of this study was to analyze by immunohistochemistry the AR and PSA (prostate-specific antigen) expression in 156 female breast carcinomas and to correlate the results with some histopathological parameters, like ER (estrogen receptor), PR (progesterone receptor), HER2/neu, nodal and metastasis status, histological type and grade. ARs and PSA were expressed in 112/156 (72%) and respectively in 61/156 (39%) of cases and we found a positive correlation between AR and PSA expression in breast carcinomas (p
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