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Immunohistochemical investigation of neuroendocrine component in prostate adenocarcinoma

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Author(s): Prokopyk O. V. | Kuryk O. G. | Andreyev M. D.

Journal: Морфологія
ISSN 1997-9665

Volume: 4;
Issue: 3;
Start page: 39;
Date: 2010;
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Keywords: prostate adenocarcinoma | neuroendocrine differentiation | immunohistochemical investigation | chromogranin A | neuron-specific enolase

ABSTRACT
A purpose of current research was to investigate the neuroendocrine component of prostate adenocarcinoma. The immunohistochemical investigation with using markers of neuroendocine differentiation – chromogranin A and neuronspecific enolase was performed. The neuroendocrine differentiation in light-cell adenocarcinoma is more expressive comparing with poorly dark-cell adenocarcinoma, and the neuroendocrine differentiation in moderately differentiated adenocarcinoma is more expressive comparing with poorly differentiated adenocarcinoma.
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