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Immunomodulatory effect of Eupalitin-3-O-ß-D-galactopyranoside in Koi carp(Cyprinus carpio)

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Author(s): *K.A.Fathima,

Journal: Journal of Pharmacy Research
ISSN 0974-6943

Volume: 4;
Issue: 10;
Start page: 3396;
Date: 2011;
Original page

Keywords: Eupalitin-3-o-ß-D-galactopyranoside | Cyprinuscarpio | Cyclosporine A.

ABSTRACT
The aim of the present study was to evaluate the immunomodulatory effect of Eupalitin-3-o-ß-D-galactopyranoside on the immune response of Koi carp(Cyprinus carpio).Administration of 20mg/Kg body wt of Eupalitin-3-o-ß-D-galactopyranoside intramuscularly suppressed the nonspecific immune responsein Koi carp.Lymphopenia,neutrophilia and leucopenia were observed, with reduction in erythrocyte count, Serum protein, and haemoglobin. Respiratory burstactivity of neutrophils in blood was reduced. The Immunomodulatory effects of Eupalitin-3-o-ß-D -galactopyranoside were compared with the well knownImmunosuppressant Cyclosporine A.
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