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Impact of oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in oncology

Author(s): Vashi Pankaj | Trukova Kristen | Lammersfeld Carolyn | Braun Donald | Gupta Digant

Journal: Nutrition Journal
ISSN 1475-2891

Volume: 9;
Issue: 1;
Start page: 60;
Date: 2010;
Original page

Abstract Background Serum 25-hydroxyvitamin D [25(OH)D] is the major circulating form of vitamin D and a standard indicator of vitamin D status. Emerging evidence in the literature suggests a high prevalence of suboptimal vitamin D (as defined by serum 25(OH)D levels of 32 ng/ml compared to patients with baseline levels < 20 ng/ml. Conclusions The response to supplementation from suboptimal to optimal levels was greatest in patients with prostate and lung cancer as well as those with baseline levels between 20-32 ng/ml. Characteristics of non-responders as well as those who take longer to respond to supplementation need to be further studied and defined. Additionally, the impact of improved serum 25(OH)D levels on patient survival and quality of life needs to be investigated.

Tango Jona
Tangokurs Rapperswil-Jona

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