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Impact of renal capsular infiltration on disease specific survival in patients with localized renal cell carcinoma (≤pT2)

Author(s): Çetin Volkan Öztekin | Alp Özgür Akdemir | Ömer Gökhan Doluoğlu | Özgür Uğurlu | Mustafa Sungur | Mustafa Sungur

Journal: Turkish Journal of Urology
ISSN 1300-5804

Volume: 36;
Issue: 04;
Start page: 328;
Date: 2010;
Original page

Keywords: Renal capsule | renal cell carcinoma | survival.

Objective: To investigate the impact of renal capsular infiltration on disease specific survival in pathologically localized renal cell carcinoma. Materials and methods: The medical records of 89 patients with pT1-3aN0M0 renal cell carcinoma who underwent open radical nephrectomy in our institution between 2000-2009 were evaluated retrospectively. The prognostic value of renal capsular involvement was investigated with univariate and multivariate survival analyses in patients with pT1-2N0M0 disease. Results: Capsular involvement was present in 26 of 79 (32.9%) pT1-2N0M0 patients. The 3-year disease specific survival rates for patients with and without capsular infiltration were 75.4% and 97.7%, respectively (p
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