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Impact of Vitamin E Supplementation on Blood Pressure and Hs-CRP in Type 2 Diabetic Patients

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Author(s): Maryam Rafraf | Behnaz Bazyun | Mohammad Ali Sarabchian | Abdolrasoul Safaeiyan | Seyed Jamal Ghaemmaghami Hezaveh

Journal: Health Promotion Perspectives
ISSN 2228-6497

Volume: 2;
Issue: 1;
Start page: 72;
Date: 2012;
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Keywords: Vitamin E | Blood pressure | Inflammation | Type 2 diabetes

ABSTRACT
Background: Type 2 diabetes mellitus (T2DM) is a major public health problem worldwide.Hypertension and inflammation are well recognized as risk factors for the macrovascular complicationsof diabetes. The aim of this study was to assess the impact of vitamin E supplementationon blood pressure (BP), serum high-sensitivity C-reactive protein (hs-CRP) and fasting bloodglucose in patients with T2DM.Methods: In a double blind, randomized, controlled clinical trial, 83 patients with T2DM weredivided randomly into two groups of vitamin E (400 mg/d, n=42) and placebo (n=41). All patientsreceived the pearls for 8 weeks. Baseline and eighth week BP, serum hs-CRP, fasting bloodglucose, anthropometric and dietary intake data were obtained from each patient. Data were analyzedusing SPSS version 11.5.Results: Vitamin E supplementation significantly increased serum levels of vitamin E (P
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