Academic Journals Database
Disseminating quality controlled scientific knowledge

Importance of early detection of lung cancers with initial paraneoplastic manifestations

Author(s): Vukić Vera | Škodrić-Trifunović Vesna | Gvozdenović Branislav S. | Jovanović Dragana | Žunić Miodrag | Đurić Dušan

Journal: Srpski Arhiv za Celokupno Lekarstvo
ISSN 0370-8179

Volume: 138;
Issue: 9-10;
Start page: 595;
Date: 2010;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: lung cancer | radiography | clinical stage | paraneoplastic syndromes

Introduction. Lung cancers are mostly detected in the developed clinical stages, with clearly manifested pulmonary, extrapulmonary or metastatic manifestations. In the early disease stages, radiographic and clinical manifestations may be absent or mimicked. Objective. The aim of this study was the timely detection of early pulmonary, extrapulmonary and paraneoplastic manifestations of lung cancers in order to apply the most appropriate treatment protocols. Methods. We examined 230 patients with lung cancer, among them 125 of the working study group with minimal pulmonary and/or initial paraneoplastic symptoms, and 105 patients in the control group with clear tumour manifestations. Results. The symptom analysis revealed a statistically significantly lesser presence of the respiratory symptoms in the working study group (68%) in comparison with the control group of patients (97%) (c2=29.996; p0.05), and a positive bronchoscopic finding of the centrally localized tumour (mainly right upper lobe) was confirmed in patients of both groups with normal radiographic findings. The number of diagnosed patients in earlier clinical disease stages (I, II, IIIa) with better prognosis in non-small cell lung cancer was significantly higher (c2=19.149; p
Why do you need a reservation system?      Save time & money - Smart Internet Solutions