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Incidence and Risk Factors of the Secondary Skin Infections in Patients with Radiodermatitis

Author(s): Ulku Altoparlak | Ozlem Koca | Timur Koca

Journal: Eurasian Journal of Medicine
ISSN 1308-8734

Volume: 43;
Issue: 03;
Start page: 177;
Date: 2011;
Original page

Keywords: Colonization | Radiodermatitis | Risk factors | Secondary skin infection

Objective: The aim of this prospective study was to investigate the incidence and risk factors of secondary infected radiodermatitis in patients receiving radiotherapy and to determine isolated microorganisms’ resistance profiles to different antimicrobial agents.Materials and Methods: The study comprised 62 patients admitted to the Regional Training and Research Hospital from January 2009 to January 2010. Radiodermatitis was graded according to the National Cancer Institute’s Common Toxicity Criteria version 3.0. Potential risk factors for secondary infection were recorded and evaluated by univariate and multivariate analyses.Results: In 62 patients, grade 1, 2, 3 and 4 radiodermatitis were observed in 33 (53.2%), 11 (17.7%), 8 (12.9%) and 10 (16.2%) patients, respectively. Skin infection secondary to radiodermatitis occurred in 14 patients (infected patients), 21.4%, 21.4% and 57.2% of whom had grade 2, 3 and 4 radiodermatitis, respectively. Forty-eight patients were found to be colonized with micoorganisms (colonized patients). In the univariate analysis, concurrent endocrine therapy and radiodermatitis grade differed significantly between infected and colonized patients (p
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