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Induced dwarf mutant in Catharanthus roseus with enhanced antibacterial activity

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Author(s): Verma A | Singh R

Journal: Indian Journal of Pharmaceutical Sciences
ISSN 0250-474X

Volume: 72;
Issue: 5;
Start page: 655;
Date: 2010;
Original page

Keywords: Antibacterial activity | catharanthus roseus | leaf extracts | mutant

ABSTRACT
Evaluation of an ethyl methane sulphonate-induced dwarf mutant of Catharanthus roseus (L.) G. Don revealed that the mutant exhibited marked variation in morphometric parameters. The in vitro antibacterial activity of the aqueous and alcoholic leaf extracts of the mutant and control plants was investigated against medically important bacteria. The mutant leaf extracts showed enhanced antibacterial activity against all the tested bacteria except Bacillus subtilis.
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