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Induction of Heat Shock Protein Expression in Cervical Epithelial Cells by Human Semen

Author(s): J. C. Jeremias | A. M. Bongiovanni | S. S. Witkin

Journal: Infectious Diseases in Obstetrics & Gynecology
ISSN 1064-7449

Volume: 7;
Issue: 1-2;
Start page: 17;
Date: 1999;
Original page

Objective: The 70kD heat shock protein (Hsp70), induced when cells are subjected to environmental stress, prevents the denaturation and incorrect folding of polypeptides and may expedite replication and transmission of DNA and RNA viruses. We analyzed whether messenger RNA (mRNA) for Hsp70 was expressed following exposure of a cultured human cervical cell line (HeLa cells) to human semen or in cervical cells from sexually active women.
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