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Infertility improved by etanercept in ankylosing spondylitis

Author(s): Rezvani Aylin | Ozaras Nihal

Journal: Indian Journal of Pharmacology
ISSN 0253-7613

Volume: 40;
Issue: 6;
Start page: 276;
Date: 2008;
Original page

Keywords: Ankylosing spondylitis | etanercept | infertility | TNF-α

The effect of TNF-α and TNF-α antagonists on semen quality in men is controversial. TNF-α levels are usually low in seminal plasma, but they tend to increase in inflammatory and infectious diseases. Etanercept is a highly-specific antagonist of TNF-α. In this report, we describe the development of pregnancy in a couple with a previously infertile husband, who received etanercept for ankylosing spondylitis.
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