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Inflammatory myofibroblastic tumour of maxilla

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Author(s): Deshingkar S | Tupkari J | Barpande S

Journal: Journal of Oral and Maxillofacial Pathology
ISSN 0973-029X

Volume: 11;
Issue: 2;
Start page: 76;
Date: 2007;
Original page

Keywords: Inflammatory myofibroblastic tumour | inflammatory pseudotumour | maxilla

ABSTRACT
Inflammatory myofibroblastic tumour (IMT) is a biologically controversial entity that was originally described as non-neoplastic lesion in the lungs and designated initially as inflammatory pseudotumour. The lesion has recently been recognized to occur at various sites but rarely affects head and neck region. Controversies still exist regarding its reactive versus neoplastic nature. The lesion has a potential for recurrence, persistent local growth, progression to frank sarcoma and metastasis. Hence IMT can best be regarded as a low-grade sarcoma. A case of a 30-year-old female with swelling in the right maxilla and associated ophthalmic manifestations is discussed here. Contribution of immunohistochemistry for diagnosis of IMT is emphasized. Additional cytogenetic studies of this highly enigmatic and minimally studied tumour are warranted.
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