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Influence of duration of menopause, anthropometric and hormonal parameters on metabolic syndrome

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Author(s): Simoncig-Netjasov Aleksandra | Vujović Svetlana | Ivović Miomira | Tančić-Gajić Milina | Drezgić Milka

Journal: Medicinski Pregled
ISSN 0025-8105

Volume: 63;
Issue: 1-2;
Start page: 33;
Date: 2010;
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Keywords: Menopause | Anthropometry | Hormones + blood | Metabolic Syndrome X | Obesity | Hypertension | Risk Factors | Female

ABSTRACT
Introduction. Hypoestrogenic status in the menopausal women shows a shift to a central android fat distribution and metabolic syndrome (MS). Related metabolic changes and hypertension increase the risk for cardiovascular (CV) diseases. The aim of this study was to investigate the influence of duration of menopause, anthropometric and hormonal parameters on metabolic syndrome. Material and methods. 50 obese women were examined with BMI=31.92±5.83 kg/m2, age 54.40±3.64, time since menopause 5.90±5.46 years. Control group consisted of 37 normal weight women with BMI=23.50±2.13 kg/m2, age 53.92±3.95, time since menopause 5.96±4.92 years. Anthropometric characteristics and blood pressure were measured. Blood was taken at 8 am for: fasting glucose, triglycerides, cholesterol, HDL, LDL, apolipoprotein A (ApoA), apolipoprotein B (ApoB), lipoprotein(a) (Lp(a)), C-reactive protein (CRP), fibrinogen, FSH, LH, prolactin, estradiol, progesterone, testosterone and sex hormone binding globulin (SHBG). Results. In obese women significant negative correlations were found for: BMI and HDL (p
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