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Inhibition of salivary peroxidase by cigarette smoke

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Author(s): Reyhaneh Sariri | Aabdolali Varasteh | Ali Erfani | Afsaneh Rezaei | Zahra Heidari

Journal: Health
ISSN 1949-4998

Volume: 02;
Issue: 04;
Start page: 347;
Date: 2010;
Original page

Keywords: Cigarette Smoke; Oxidative Stress; Peroxidase | Saliva; Free Radicals.

ABSTRACT
Saliva is the first biological fluid to encounter many dangerous chemicals present in cigarette smoke. The oral peroxidase system is responsible for the antioxidant capacity of saliva. In this research, the interaction of cigarette smoke and oral peroxidase in smokers and non-smoers was compared. It was found that after smoking one cigarette, oral peroxidase activity was decreased in both groups: 42.5% in smokers and 58.5% in non-smokers (p < 0.05). After 30 min, the level of activity returned to 90-100% of the pre- smoking level, mainly due to the secretion of new saliva.

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